Texture Extraction Techniques for the Classification of Vegetation Species in Hyperspectral Imagery: Bag of Words Approach Based on Superpixels

Texture information allows characterizing the regions of interest in a scene. It refers to the spatial organization of the fundamental microstructures in natural images. Texture extraction has been a challenging problem in the field of image processing for decades. In this paper, different techniques based on the classic Bag of Words (BoW) approach for solving the texture extraction problem in the case of hyperspectral images of the Earth surface are proposed. In all cases the texture extraction is performed inside regions of the scene called superpixels and the algorithms profit from the information available in all the bands of the image. The main contribution is the use of superpixel segmentation to obtain irregular patches from the images prior to texture extraction. Texture descriptors are extracted from each superpixel. Three schemes for texture extraction are proposed: codebook-based, descriptor-based, and spectral-enhanced descriptor-based. The first one is based on a codebook generator algorithm, while the other two include additional stages of keypoint detection and description. The evaluation is performed by analyzing the results of a supervised classification using Support Vector Machines (SVM), Random Forest (RF), and Extreme Learning Machines (ELM) after the texture extraction. The results show that the extraction of textures inside superpixels increases the accuracy of the obtained classification map. The proposed techniques are analyzed over different multi and hyperspectral datasets focusing on vegetation species identification. The best classification results for each image in terms of Overall Accuracy (OA) range from 81.07% to 93.77% for images taken at a river area in Galicia (Spain), and from 79.63% to 95.79% for a vast rural region in China with reasonable computation timesThis work was supported in part by the Civil Program UAVs Initiative, promoted by the Xunta de Galicia and developed in partnership with the Babcock Company to promote the use of unmanned technologies in civil services. We also have to acknowledge the support by Ministerio de Ciencia e Innovación, Government of Spain (grant number PID2019-104834GB-I00), and Consellería de Educación, Universidade e Formación Profesional (ED431C 2018/19, and accreditation 2019-2022 ED431G-2019/04). All are cofunded by the European Regional Development Fund (ERDF)S

La enseñanza problematizada de la física cuántica en el nivel introductorio. Una propuesta fundamentada

La investigación didáctica no ha llegado a un consenso sobre cómo se deben abordar los cursos introductorios de física cuántica, tanto en lo referente a los contenidos que se deben enseñar como a la interpretación física de modelos fundamentales como la dualidad onda-partícula. Ante la falta de consenso, hemos llevado a cabo un estudio histórico y didáctico que nos ha permitido establecer las ideas clave de un modelo cuántico de emisión y absorción de radiación con la capacidad explicativa suficiente para que valga la pena ser enseñado. Así mismo, hemos identificado las ideas clave de un modelo de quántum que explica el comportamiento de los electrones y los fotones, lo que nos permite superar la crisis que ocasionó en la física la introducción del modelo cuántico de emisión y absorción de radiación. Aprovechando los problemas que históricamente llevaron al establecimiento de estos modelos, hemos diseñado la unidad problematizada para la enseñanza de la física cuántica en el bachillerato que presentamos en este artículo, haciendo especial hincapié en los grandes pasos que llevan a los estudiantes construir los modelos propuestos

Teaching introductory quantum physics through a problem based unit. A reasoned proposal

La investigación didáctica no ha llegado a un consenso sobre cómo se deben abordar los cursos introductorios de física cuántica, tanto en lo referente a los contenidos que se deben enseñar como a la interpretación física de modelos fundamentales como la dualidad onda-partícula. Ante la falta de consenso, hemos llevado a cabo un estudio histórico y didáctico que nos ha permitido establecer las ideas clave de un modelo cuántico de emisión y absorción de radiación con la capacidad explicativa suficiente para que valga la pena ser enseñado. Así mismo, hemos identificado las ideas clave de un modelo de quántum que explica el comportamiento de los electrones y los fotones, lo que nos permite superar la crisis que ocasionó en la física la introducción del modelo cuántico de emisión y absorción de radiación. Aprovechando los problemas que históricamente llevaron al establecimiento de estos modelos, hemos diseñado la unidad problematizada para la enseñanza de la física cuántica en el bachillerato que presentamos en este artículo, haciendo especial hincapié en los grandes pasos que llevan a los estudiantes construir los modelos propuestos.Didactic research has not reached a consensus on how introductory quantum physics courses should be addressed, both in relation to the content to be taught as in the physical interpretation of key models such as the wave-particle duality. In the absence of consensus, we conducted a historical and didactic study aiming at establishing the key ideas of a quantum model of emission and absorption of radiation with sufficient explanatory power to make it worthwhile. We also identified the key ideas of a model for quantums that can explain the behaviour of electrons and photons and which allow us to overcome the crisis produced by the introduction of the quantum model of emission and absorption of radiation. Taking into account the problems that historically led to the establishment of these models, we designed the problem based unit for teaching quantum physics in high school that we present in this article, paying special attention to the great steps that drive students to build the proposed models

The global contribution of soil mosses to ecosystem services

Soil mosses are among the most widely distributed organisms on land. Experiments and observations suggest that they contribute to terrestrial soil biodiversity and function, yet their ecological contribution to soil has never been assessed globally under natural conditions. Here we conducted the most comprehensive global standardized field study to quantify how soil mosses influence 8 ecosystem services associated with 24 soil biodiversity and functional attributes across wide environmental gradients from all continents. We found that soil mosses are associated with greater carbon sequestration, pool sizes for key nutrients and organic matter decomposition rates but a lower proportion of soil-borne plant pathogens than unvegetated soils. Mosses are especially important for supporting multiple ecosystem services where vascular-plant cover is low. Globally, soil mosses potentially support 6.43 Gt more carbon in the soil layer than do bare soils. The amount of soil carbon associated with mosses is up to six times the annual global carbon emissions from any altered land use globally. The largest positive contribution of mosses to soils occurs under a high cover of mat and turf mosses, in less-productive ecosystems and on sandy and salty soils. Our results highlight the contribution of mosses to soil life and functions and the need to conserve these important organisms to support healthy soils.The study work associated with this paper was funded by a Large Research Grant from the British Ecological Society (no. LRB17\1019; MUSGONET). D.J.E. is supported by the Hermon Slade Foundation. M.D.-B. was supported by a Ramón y Cajal grant from the Spanish Ministry of Science and Innovation (RYC2018-025483-I), a project from the Spanish Ministry of Science and Innovation for the I + D + i (PID2020-115813RA-I00 funded by MCIN/AEI/10.13039/501100011033a) and a project PAIDI 2020 from the Junta de Andalucía (P20_00879). E.G. is supported by the European Research Council grant agreement 647038 (BIODESERT). M.B. is supported by a Ramón y Cajal grant from Spanish Ministry of Science (RYC2021-031797-I). A.d.l.R is supported by the AEI project PID2019-105469RB-C22. L.W. and Jianyong Wang are supported by the Program for Introducing Talents to Universities (B16011) and the Ministry of Education Innovation Team Development Plan (2013-373). The contributions of T.G. and T.U.N. were supported by the Research Program in Forest Biology, Ecology and Technology (P4-0107) and the research projects J4-3098 and J4-4547 of the Slovenian Research Agency. The contribution of P.B.R. was supported by the NSF Biological Integration Institutes grant DBI-2021898. J. Durán and A. Rodríguez acknowledge support from the FCT (2020.03670.CEECIND and SFRH/BDP/108913/2015, respectively), as well as from the MCTES, FSE, UE and the CFE (UIDB/04004/2021) research unit financed by FCT/MCTES through national funds (PIDDAC)

Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination

Myelination is essential for neuronal function and health. In peripheral nerves, >100 causative mutations have been identified that cause Charcot-Marie-Tooth disease, a disorder that can affect myelin sheaths. Among these, a number of mutations are related to essential targets of the posttranslational modification neddylation, although how these lead to myelin defects is unclear. Here, we demonstrate that inhibiting neddylation leads to a notable absence of peripheral myelin and axonal loss both in developing and regenerating mouse nerves. Our data indicate that neddylation exerts a global influence on the complex transcriptional and posttranscriptional program by simultaneously regulating the expression and function of multiple essential myelination signals, including the master transcription factor EGR2 and the negative regulators c-Jun and Sox2, and inducing global secondary changes in downstream pathways, including the mTOR and YAP/TAZ signaling pathways. This places neddylation as a critical regulator of myelination and delineates the potential pathogenic mechanisms involved in CMT mutations related to neddylation

Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination

Myelination is essential for neuronal function and health. In peripheral nerves, >100 causative mutations have been identified that cause Charcot-Marie-Tooth disease, a disorder that can affect myelin sheaths. Among these, a number of mutations are related to essential targets of the posttranslational modification neddylation, although how these lead to myelin defects is unclear. Here, we demonstrate that inhibiting neddylation leads to a notable absence of peripheral myelin and axonal loss both in developing and regenerating mouse nerves. Our data indicate that neddylation exerts a global influence on the complex transcriptional and posttranscriptional program by simultaneously regulating the expression and function of multiple essential myelination signals, including the master transcription factor EGR2 and the negative regulators c-Jun and Sox2, and inducing global secondary changes in downstream pathways, including the mTOR and YAP/TAZ signaling pathways. This places neddylation as a critical regulator of myelination and delineates the potential pathogenic mechanisms involved in CMT mutations related to neddylation

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

Global hotspots for soil nature conservation

19 páginas.- 5 figuras.- 98 referencias.- Supplementary information The online version contains supplementary material available at https://doi.org/10.1038/s41586-022-05292-xSoils are the foundation of all terrestrial ecosystems1. However, unlike for plants and animals, a global assessment of hotspots for soil nature conservation is still lacking2. This hampers our ability to establish nature conservation priorities for the multiple dimensions that support the soil system: from soil biodiversity to ecosystem services. Here, to identify global hotspots for soil nature conservation, we performed a global field survey that includes observations of biodiversity (archaea, bacteria, fungi, protists and invertebrates) and functions (critical for six ecosystem services) in 615 composite samples of topsoil from a standardized survey in all continents. We found that each of the different ecological dimensions of soils—that is, species richness (alpha diversity, measured as amplicon sequence variants), community dissimilarity and ecosystem services—peaked in contrasting regions of the planet, and were associated with different environmental factors. Temperate ecosystems showed the highest species richness, whereas community dissimilarity peaked in the tropics, and colder high-latitudinal ecosystems were identified as hotspots of ecosystem services. These findings highlight the complexities that are involved in simultaneously protecting multiple ecological dimensions of soil. We further show that most of these hotspots are not adequately covered by protected areas (more than 70%), and are vulnerable in the context of several scenarios of global change. Our global estimation of priorities for soil nature conservation highlights the importance of accounting for the multidimensionality of soil biodiversity and ecosystem services to conserve soils for future generations.This project received funding from the British Ecological Society (agreement LRA17\1193; MUSGONET). C.A.G. and N.E. were funded by DFG–FZT 118, 202548816; C.A.G. was supported by FCT-PTDC/BIA-CBI/2340/2020; M.D.-B. was supported by RYC2018-025483-I, PID2020-115813RA-I00\MCIN/AEI/10.13039/501100011033 and P20_00879. M.A.M.-M. and S.A. were funded by FONDECYT 1181034 and ANID-PIA-Anillo INACH ACT192057. J.D. and A.R. acknowledge support from IF/00950/2014, 2020.03670.CEECIND, SFRH/BDP/108913/2015 and UIDB/04004/2020. Y.-R.L. was supported by 2662019PY010 from the FRFCU. L.T. was supported by the ESF grant PRG632. F.B. and J.L.M. were supported by i-LINK+2018 (LINKA20069) funded by CSIC. C.T.-D. was supported by the Grupo de Biodibersidad & Cambio Global UBB–GI 170509/EF. C.P. was supported by the EU H2020 grant agreement 101000224. H.C. was supported by NSFC32101335, FRFCU2412021QD014 and CPSF2021M690589. J.P.V. was supported by DST (DST/INT/SL/P-31/2021) SERB (EEQ/2021/001083) and BHU-IoE (6031).Peer reviewe

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children

We found that 19 (10.4%) of 183 unvaccinated children hospitalized for COVID-19 pneumonia had autoantibodies (auto-Abs) neutralizing type I IFNs (IFN-alpha 2 in 10 patients: IFN-alpha 2 only in three, IFN-alpha 2 plus IFN-omega in five, and IFN-alpha 2, IFN-omega plus IFN-beta in two; IFN-omega only in nine patients). Seven children (3.8%) had Abs neutralizing at least 10 ng/ml of one IFN, whereas the other 12 (6.6%) had Abs neutralizing only 100 pg/ml. The auto-Abs neutralized both unglycosylated and glycosylated IFNs. We also detected auto-Abs neutralizing 100 pg/ml IFN-alpha 2 in 4 of 2,267 uninfected children (0.2%) and auto-Abs neutralizing IFN-omega in 45 children (2%). The odds ratios (ORs) for life-threatening COVID-19 pneumonia were, therefore, higher for auto-Abs neutralizing IFN-alpha 2 only (OR [95% CI] = 67.6 [5.7-9,196.6]) than for auto-Abs neutralizing IFN-. only (OR [95% CI] = 2.6 [1.2-5.3]). ORs were also higher for auto-Abs neutralizing high concentrations (OR [95% CI] = 12.9 [4.6-35.9]) than for those neutralizing low concentrations (OR [95% CI] = 5.5 [3.1-9.6]) of IFN-omega and/or IFN-alpha 2

The global contribution of soil mosses to ecosystem services

DATA AVAILABILITY : All the materials, raw data, and protocols used in the article are available upon request. Data used in this study can be found in the Figshare data repository https://figshare.com/s/b152d06e53066d08b934 ref.Soil mosses are among the most widely distributed organisms on land. Experiments and observations suggest that they contribute to terrestrial soil biodiversity and function, yet their ecological contribution to soil has never been assessed globally under natural conditions. Here we conducted the most comprehensive global standardized field study to quantify how soil mosses influence 8 ecosystem services associated with 24 soil biodiversity and functional attributes across wide environmental gradients from all continents. We found that soil mosses are associated with greater carbon sequestration, pool sizes for key nutrients and organic matter decomposition rates but a lower proportion of soil-borne plant pathogens than unvegetated soils. Mosses are especially important for supporting multiple ecosystem services where vascular-plant cover is low. Globally, soil mosses potentially support 6.43 Gt more carbon in the soil layer than do bare soils. The amount of soil carbon associated with mosses is up to six times the annual global carbon emissions from any altered land use globally. The largest positive contribution of mosses to soils occurs under perennial, mat and turf mosses, in less-productive ecosystems and on sandy soils. Our results highlight the contribution of mosses to soil life and functions and the need to conserve these important organisms to support healthy soils.A Large Research Grant from the British Ecological Society; the Hermon Slade Foundation; a Ramón y Cajal grant from the Spanish Ministry of Science and Innovation; the Junta de Andalucía; the European Research Council; the AEI; the Program for Introducing Talents to Universities; the Ministry of Education Innovation Team Development Plan; the Research Program in Forest Biology, Ecology and Technology; the Slovenian Research Agency; the NSF Biological Integration Institutes; the FCT and FCT/MCTES through national funds (PIDDAC).http://www.nature.com/ngeo/hj2024BiochemistryGeneticsMicrobiology and Plant PathologySDG-15:Life on lan